Senior Manager, Clinical Informatics

McKesson
McKesson

USD 134,700-224,500 / year

Posted on Sep 10, 2026

Senior Manager, Clinical Informatics

Remote - Texas Job ID JR0153117 Category Data Scientist, Information Technology Post Date Sep. 10, 2026

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Ontada is poised to transform the fight against cancer and make a true difference in the treatment of oncology patients. Backed by the strength of a Fortune 8 company, our entrepreneurial organization develops technologies and services used by the oncology community to deliver evidence-based, personalized care, providing insights used by biopharma companies to accelerate drug development and support the entire treatment journey. Our work powers informed clinical decision-making at every pivotal moment in oncology – from initial diagnoses to complex clinical decision support.

The Senior Manager, Clinical Informatics leads a specialized team within the Clinical Informatics organization responsible for the delivery and ongoing support of assigned clinical content, terminology, analytics, AI-enabled, and other informatics initiatives. This role is accountable for team performance, execution, quality, resource planning, and operational outcomes within the area of responsibility.

The Senior Manager translates department strategy and priorities into team-level plans, ensures successful execution of projects and operational commitments, and develops team capabilities. Working within the Clinical Informatics Leadership Team and with Product, Engineering, Clinical, and business stakeholders, this role focuses on delivering high-quality results through effective leadership and operational excellence.

Key Responsibilities

  • Team Leadership & Development: Manage the day-to-day activities, priorities, and performance of direct reports; provide coaching, feedback, performance management, and career development support; allocate resources and balance workloads across competing priorities; and build team capability through training, mentoring, and succession planning.

  • Operational Execution & Delivery: Lead the execution of projects, operational initiatives, and ongoing support activities within the assigned area of responsibility; monitor delivery timelines, quality measures, operational metrics, and customer commitments; identify risks, dependencies, and resource constraints and escalate as appropriate; implement and continuously improve processes, standards, and best practices; and ensure delivery outcomes meet established business and operational objectives.

  • Clinical Informatics & Content Operations: Oversee the maintenance, quality, and continuous improvement of clinical content assets, terminology mappings, data standards, and informatics solutions; ensure adherence to governance, quality, compliance, and operational requirements; support automation and process improvement initiatives that enhance efficiency, scalability, and data quality; and coordinate issue resolution and remediation activities within assigned domains.

  • Analytics, AI, and Data Solutions: Lead the delivery of analytics, reporting, machine learning, and AI-assisted solutions within the assigned area of responsibility; monitor performance, adoption, and effectiveness of delivered solutions; ensure work products meet business requirements and quality standards; and leverage operational and performance data to identify trends, opportunities, and areas for continuous improvement.

  • Stakeholder Collaboration: Partner with Product, Engineering, Clinical, Customer Success, Quality, and other stakeholders to execute agreed-upon priorities; communicate team progress, risks, dependencies, and outcomes; and support cross-functional initiatives and organizational objectives through effective collaboration and stakeholder engagement.

Minimum Requirement

Degree or equivalent experience. Typically requires 9+ years of professional experience and 1+ years of supervisory and/or management experience.

Education

Bachelor’s degree in Nursing, Pharmacy, Health Informatics, Healthcare Administration, Life Sciences, or a related field

Critical Skills

  • Clinical licensure or other applicable clinical credential

  • 10+ years of progressive healthcare, clinical informatics, clinical content, healthcare data, or related experience

  • 3+ years of experience in clinical content management, EHR systems, clinical decision support, or related disciplines

  • 3+ years of direct people leadership experience, including performance management, coaching, goal setting, and employee development

  • Experience leading cross-functional initiatives involving clinical, product, engineering, operations, and/or customer-facing teams

  • Experience translating business or clinical requirements into operational processes, content solutions, data products, or technology-enabled workflows

  • Demonstrated ability to prioritize competing work, allocate resources, and deliver results in a fast-paced environment

Preferred qualifications

  • Master’s degree in Nursing Informatics, Health Informatics, Healthcare Administration, Pharmacy, Public Health, Data Science, or related field

  • Board certification in Clinical Informatics, Nursing Informatics, Pharmacy Informatics, or related specialty

  • Experience with terminologies and standards including but not limited to SNOMED CT, LOINC, ICD-10, CPT, HCPCS, RxNorm, HL7, FHIR.

  • Experience implementing AI, analytics, automation, or machine learning solutions in healthcare settings

All candidates must be authorized to work in the U.S. No sponsorship or relocation is available for this position.

This position offers the possibility of a hybrid work arrangement based on recent updates to our in-office/work‑from‑home model. If located in DFW area, the selected candidate may be expected to work on‑site at our Las Colinas office a minimum of two (2) days per week, with the remaining days worked remotely. Specific in‑office days may be designated according to team needs and business priorities.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here. (opens in new window)

Our Base Pay Range for this position

$134,700 - $224,500

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com (opens in new window).

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity (opens in new window) page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com (opens in new window) or (Canada) Accessibility@mckesson.ca (opens in new window). Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!