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Senior Scientist/Principal Scientist Immuno-Oncology

Kernal Biologics

Kernal Biologics

Cambridge, MA, USA
Posted on Thursday, August 17, 2023

Job Summary:

Kernal is seeking a Senior Scientist / Principal Scientist who wishes to play a key role in advancing novel immunotherapy drug candidates to the clinic. The ideal candidate will act as resource in Immuno-Oncology across the organization and is looking to make an impact in a biotech startup environment.


  • Responsible for initiating, planning and executing experiments that supports projects relevant to cancer immunotherapy and immunology
  • Perform various in vitro and ex-vivo assays utilizing cellular, molecular and translational biology techniques
  • Design and executing in vivo studies to assess preclinical efficacy of Kernal proprietary mRNAs
  • Generate, analyze and interpret research data and oversee proper documentation and scientific findings. Must be willing to work at the bench.
  • Supervise and mentor junior staff


  • Doctorate in Immunology, Oncology or relevant scientific discipline with a strong publication record.
  • Experience post Ph.D. in pharmaceutical or biotechnology settings is highly desired. 2+ (Senior Scientist), 5+ years (Principal Scientist)
  • Expertise in drug discovery in oncology / immunology related projects
  • Experience in biochemical and cell-based assays (FACS, Flow cytometry, western blot, ELISA, single cell RNAseq, ICS etc…)
  • Expertise with tumor models (syngeneic, GEMM, humanized)
  • Ability to work in a fast paced environment with ambitious goals in a growing biotech


  • Competitive compensation package
  • Excellent healthcare coverage
  • Highly competitive 401(k)
  • Flexible Spending Account (FSA)
  • Generous vacation and sick days
  • Paid parental leave, family caregiver leave, medical leave
  • Comprehensive insurance coverage
  • On-site cafe with complementary snacks and drinks
  • Monthly subway pass, or a subsidized commuter rail pass
  • Free MIT athletics gym membership
  • Free Bluebikes membership