Senior Associate Scientist, Hybridoma and B Cell Antibody Discovery
Pfizer
What You Will Achieve
Biomedicine Design’s Endogenous Antibody Discovery Group is seeking a Senior Associate Scientist to support hybridoma-based antibody discovery projects and related workflows. The role requires joining other group members to carry out therapeutic antibody discovery campaigns employing immunization of rodents and hybridoma generation, in coordination with other discovery methods such as FACS and immune library generation and panning. In particular, the role requires carrying out all established workflows associated with hybridoma-based antibody discovery, including selection of rodents (wildtype and transgenic) as hosts for immunization; immunizations (protein, cell-based and genetic); evaluation of serum responses by ELISA; electro-cell fusion; hybridoma culture and screening; and VH-VL molecular cloning. Finally, the role requires evaluation and integration of new technologies related to hybridoma generation and therapeutic antibody discovery, in coordination with other group members.
How You Will Achieve It
End-to-end support of hybridoma campaigns for lead therapeutic antibody discovery.
Monitoring and maintaining stocks of reagents required for hybridoma workflows.
Preparation and presentation of reports summarizing outputs of hybridoma campaigns.
Qualifications
Must-Have
BSc degree with 3+ years of experience with wet lab and working full time in a university or industry lab setting OR Masters Degree with 0+ years of experience with wet lab experience.
Experience with primary cell culture and aseptic techniques.
Experience with molecular biology techniques, including PCR.
Experience working with rodents, in particular mice.
Excellent communication skills, written and oral.
Nice-to-Have
Experience with flow cytometry.
Experience with laboratory automation.
Experience working with hybridomas.
PHYSICAL/MENTAL REQUIREMENTS
Lifting, sitting, standing, walking, bending, ability to do math and calculations, ability to perform data analysis.
Work Location Assignment: On Premise. On Premise colleagues work in a Pfizer site because it’s needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site.
Other Job Details
Last Date to Apply: December 7th, 2023.
The annual base salary for this position ranges from $62,800.00 to $104,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.